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BDBM132193 USRE45173, 132A

SMILES: Cc1ccncc1N1CCN(C1=O)c1ccc2nn(C)cc2c1

InChI Key: InChIKey=LTKWZFZWLLMHMY-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 132193   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 17A1


(Homo sapiens (Human))
BDBM132193
PNG
(USRE45173, 132A)
Show SMILES Cc1ccncc1N1CCN(C1=O)c1ccc2nn(C)cc2c1
Show InChI InChI=1S/C17H17N5O/c1-12-5-6-18-10-16(12)22-8-7-21(17(22)23)14-3-4-15-13(9-14)11-20(2)19-15/h3-6,9-11H,7-8H2,1-2H3
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PC sid
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Similars

US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



Novartis AG

US Patent


Assay Description
Cytochrome P450, 17-20 lyase (CYP17-lyase) assay development using recombinant human CYP17 enzyme and 17-alpha -hydroxy pregnenolone [21-3H] as the s...


US Patent USRE45173 (2014)


BindingDB Entry DOI: 10.7270/Q2MW2FT2
More data for this
Ligand-Target Pair