BDBM132406 US8841312, 153

SMILES CN(C)C1CCN(CC1)c1ccc(Nc2ncc3c4ccnc(Cl)c4n(C4CCCC4)c3n2)nc1

InChI Key InChIKey=LQLWCEYRAKKEIP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 132406   

TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM132406(US8841312, 153)
Affinity DataIC50:  2.80nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM132406(US8841312, 153)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:The Cdk4 and Cdk6 inhibitory activity of the compounds is measured with a kinase inhibition assay using recombinant Cdk4/CyclinD1 or Cdk6/CyclinD3 pr...More data for this Ligand-Target Pair
In DepthDetails US Patent