BindingDB logo
myBDB logout

BDBM132779 US8846746, 45

SMILES: CCCCc1cccc(c1)-c1cc(NC(=O)[C@H]2CNC(=O)C2)nn1-c1ccccc1

InChI Key: InChIKey=HVQKRIPYZSSZOV-TWYLJJHKNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 132779   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium/glucose cotransporter 1 (SGLT1)


(Homo sapiens (Human))
BDBM132779
PNG
(US8846746, 45)
Show SMILES CCCCc1cccc(c1)-c1cc(NC(=O)[C@H]2CNC(=O)C2)nn1-c1ccccc1
Show InChI InChI=1/C24H26N4O2/c1-2-3-8-17-9-7-10-18(13-17)21-15-22(26-24(30)19-14-23(29)25-16-19)27-28(21)20-11-5-4-6-12-20/h4-7,9-13,15,19H,2-3,8,14,16H2,1H3,(H,25,29)(H,26,27,30)/t19-/s2
UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 4.30n/an/an/an/an/a37



Japan Tobacco Inc

US Patent


Assay Description
The stable cell line expressing human SGLT1 was seeded at 5x104 cells/well on BioCoat Poly-D-Lysine 96 well plate with Lid (Becton Dickinson and Comp...


US Patent US8846746 (2014)


BindingDB Entry DOI: 10.7270/Q27M06MJ
More data for this
Ligand-Target Pair