BDBM13286 4-Hydroxy-3-[3-(S)-(7-methoxynaphthalen-2-ylsulfonylamino)-2-oxopyrrolidin-1-ylmethyl]benzamidine::4-hydroxy-3-{[(3S)-3-[(7-methoxynaphthalene-2-)sulfonamido]-2-oxopyrrolidin-1-yl]methyl}benzene-1-carboximidamide::CHEMBL93854::Sulfonamidopyrrolidinone 20a
SMILES COc1ccc2ccc(cc2c1)S(=O)(=O)N[C@H]1CCN(Cc2cc(ccc2O)C(N)=N)C1=O
InChI Key InChIKey=WYPLWOJSDQFHPG-FQEVSTJZSA-N
Data 9 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 13286
Affinity DataKi: 3nM ΔG°: -11.5kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Binding affinity against serine protease Coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 3.16nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
Affinity DataKi: 206nMAssay Description:Binding affinity against thrombinMore data for this Ligand-Target Pair
Affinity DataKi: 305nM ΔG°: -8.79kcal/molepH: 7.5 T: 2°CAssay Description:The enzyme reactions were initiated by the addition of substrate, and the color developed from the release of p-nitroanilide from each chromogenic su...More data for this Ligand-Target Pair
Affinity DataKi: 305nMAssay Description:Binding affinity against trypsinMore data for this Ligand-Target Pair
Affinity DataKi: 1.07E+3nMAssay Description:Binding affinity against tissue plasminogen activator (t-Pa)More data for this Ligand-Target Pair
Affinity DataKi: 1.97E+3nMAssay Description:Binding affinity against activated protein C (APC)More data for this Ligand-Target Pair
Affinity DataKi: 2.35E+3nMAssay Description:Binding affinity against plasminMore data for this Ligand-Target Pair