BDBM133661 US8846711, 5::US9051321, 5

SMILES CC(C)(C)OC(=O)N1CCC(COc2ccc(F)cc2)CC1

InChI Key InChIKey=KBJPEEKMTGAFKO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 133661   

TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
Fab Pharma

US Patent
LigandPNGBDBM133661(US8846711, 5 | US9051321, 5)
Affinity DataIC50:  250nMpH: 6.5 T: 2°CAssay Description:The assay buffer "AB" contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
Fab Pharma

US Patent
LigandPNGBDBM133661(US8846711, 5 | US9051321, 5)
Affinity DataIC50:  250nMpH: 6.5 T: 2°CAssay Description:Compound inhibitory activity of FabI enzyme is measured in vitro by the IC5 so determination using a fluorescence based assay.The protein FabI from S...More data for this Ligand-Target Pair
In DepthDetails US Patent