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BDBM133968 US8846929, 367

SMILES: CCOC(=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3C2CCC(C)(C)CC2)c1=O

InChI Key: InChIKey=QXDBMXZCFGSMQZ-AERCQKQUNA-N

Data: 1 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 133968   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Opioid growth factor receptor-like protein 1


(Homo sapiens (Human))
BDBM133968
PNG
(US8846929, 367)
Show SMILES CCOC(=O)c1nc2ccccc2n([C@@H]2C[C@@H]3CCC[C@H](C2)N3C2CCC(C)(C)CC2)c1=O
Show InChI InChI=1/C27H37N3O3/c1-4-33-26(32)24-25(31)30(23-11-6-5-10-22(23)28-24)21-16-19-8-7-9-20(17-21)29(19)18-12-14-27(2,3)15-13-18/h5-6,10-11,18-21H,4,7-9,12-17H2,1-3H3/t19-,20+,21+
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
374n/an/an/an/an/an/a7.4n/a



Purdue Pharma LP

US Patent


Assay Description
Radioligand binding assays (screening and dose-displacement) used 0.1nM [3H]-nociceptin (NEN; 87.7 Cl/nimole) with 10-20 ug membrane protein in a fin...


US Patent US8846929 (2014)


BindingDB Entry DOI: 10.7270/Q2G44P04
More data for this
Ligand-Target Pair