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BDBM134303 US8846658, 13

SMILES: CC1(COCC(N)=N1)c1cccc(NC(=O)c2ccccn2)c1

InChI Key: InChIKey=FFUNHRRXZYUZCU-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 134303   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Beta-secretase 1


(Homo sapiens (Human))
BDBM134303
PNG
(US8846658, 13)
Show SMILES CC1(COCC(N)=N1)c1cccc(NC(=O)c2ccccn2)c1
Show InChI InChI=1/C17H18N4O2/c1-17(11-23-10-15(18)21-17)12-5-4-6-13(9-12)20-16(22)14-7-2-3-8-19-14/h2-9H,10-11H2,1H3,(H2,18,21)(H,20,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 3.40E+3n/an/an/an/a4.525



Novartis AG

US Patent


Assay Description
Recombinant BACE-1 (extracellular domain, expressed in baculovirus and purified using standard methods) at 0.1 to 10 nM concentrations is incubated w...


US Patent US8846658 (2014)


BindingDB Entry DOI: 10.7270/Q2PN94BX
More data for this
Ligand-Target Pair