BDBM13469 ({4-[(2S)-2-carbamoyl-2-[(2S)-2-(1-{4-[difluoro(phosphono)methyl]phenyl}acetamido)-3-phenylpropanamido]ethyl]phenyl}difluoromethyl)phosphonic acid::Difluoromethylphosphonic acid (DFMP) deriv. 1::[[4-[[(1S)-1-[[(1S)-1-aminocarbonyl-2-[4-(difluoro-phosphono-methyl)phenyl]ethyl]carbamoyl]-2-phenyl-ethyl]carbamoylmethyl]phenyl]-difluoro-methyl]phosphonic acid
SMILES NC(=O)[C@H](Cc1ccc(cc1)C(F)(F)P(O)(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)Cc1ccc(cc1)C(F)(F)P(O)(O)=O
InChI Key InChIKey=LGZYIQKUXWAUAL-GOTSBHOMSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 13469
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Qilu University Of Technology
Curated by ChEMBL
Qilu University Of Technology
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Inhibition of human PTP1B catalytic domain expressed in Escherichia coli assessed as pNPP hydrolysis measured every 30 secs for 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMpH: 7.0 T: 2°CAssay Description:The activity of PTP1B enzyme was assayed with 4-nitrophenyl phosphate (pNPP) as substrate. Rate of formation of the phenolate ion was monitored at 41...More data for this Ligand-Target Pair