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BDBM134895 US8846698, 376

SMILES: CC(C)n1cc(C(=O)c2cncc(NC(=O)Cc3cnccn3)c2)c2cncnc12

InChI Key: InChIKey=DQKSTADLGZXHJG-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 134895   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
High affinity nerve growth factor receptor


(Homo sapiens (Human))
BDBM134895
PNG
(US8846698, 376)
Show SMILES CC(C)n1cc(C(=O)c2cncc(NC(=O)Cc3cnccn3)c2)c2cncnc12
Show InChI InChI=1S/C21H19N7O2/c1-13(2)28-11-18(17-10-24-12-26-21(17)28)20(30)14-5-16(9-23-7-14)27-19(29)6-15-8-22-3-4-25-15/h3-5,7-13H,6H2,1-2H3,(H,27,29)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 5.10E+3n/an/an/an/an/an/a



Pfizer Inc

US Patent


Assay Description
Isolated TRK Enzyme assays use the HTRF KinEASE-TK kit (Cisbio Cat# 62TK0PEJ) with recombinant His-tagged cytoplasmic domains of each TRK receptor so...


US Patent US8846698 (2014)


BindingDB Entry DOI: 10.7270/Q2F47MTW
More data for this
Ligand-Target Pair