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BDBM135715 US10179804, Example 100::US8846601, 100::US9458201, 100

SMILES: CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCS(C)(=O)=O)NC1=O)C(N)=O

InChI Key: InChIKey=XGWSOOKGTZEXOP-RYWHQVOLNA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 135715   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM135715
PNG
(US10179804, Example 100 | US8846601, 100 | US94582...)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCS(C)(=O)=O)NC1=O)C(N)=O
Show InChI InChI=1/C49H72N16O11S/c1-28(66)59-34(16-9-22-56-48(51)52)42(69)62-36-18-19-40(67)55-21-8-15-33(41(50)68)60-47(74)39(26-30-27-58-32-14-7-6-13-31(30)32)65-43(70)35(17-10-23-57-49(53)54)61-46(73)38(25-29-11-4-3-5-12-29)64-45(72)37(63-44(36)71)20-24-77(2,75)76/h3-7,11-14,27,33-39,58H,8-10,15-26H2,1-2H3,(H2,50,68)(H,55,67)(H,59,66)(H,60,74)(H,61,73)(H,62,69)(H,63,71)(H,64,72)(H,65,70)(H4,51,52,56)(H4,53,54,57)/t33-,34-,35-,36-,37-,38+,39-/s2
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
8n/an/an/an/an/an/a7.5n/a



Palatin Technologies, Inc.

US Patent


Assay Description
A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...


US Patent US8846601 (2014)


BindingDB Entry DOI: 10.7270/Q2SF2TWK
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM135715
PNG
(US10179804, Example 100 | US8846601, 100 | US94582...)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCS(C)(=O)=O)NC1=O)C(N)=O
Show InChI InChI=1/C49H72N16O11S/c1-28(66)59-34(16-9-22-56-48(51)52)42(69)62-36-18-19-40(67)55-21-8-15-33(41(50)68)60-47(74)39(26-30-27-58-32-14-7-6-13-31(30)32)65-43(70)35(17-10-23-57-49(53)54)61-46(73)38(25-29-11-4-3-5-12-29)64-45(72)37(63-44(36)71)20-24-77(2,75)76/h3-7,11-14,27,33-39,58H,8-10,15-26H2,1-2H3,(H2,50,68)(H,55,67)(H,59,66)(H,60,74)(H,61,73)(H,62,69)(H,63,71)(H,64,72)(H,65,70)(H4,51,52,56)(H4,53,54,57)/t33-,34-,35-,36-,37-,38+,39-/s2
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
US Patent
8n/an/an/an/an/an/an/an/a



Palatin Technologies, Inc.

US Patent


Assay Description
Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...


US Patent US10179804 (2019)


Article DOI: 10.1074/jbc.M702316200
BindingDB Entry DOI: 10.7270/Q24T6MFP
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM135715
PNG
(US10179804, Example 100 | US8846601, 100 | US94582...)
Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CCC(=O)NCCC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CCS(C)(=O)=O)NC1=O)C(N)=O
Show InChI InChI=1/C49H72N16O11S/c1-28(66)59-34(16-9-22-56-48(51)52)42(69)62-36-18-19-40(67)55-21-8-15-33(41(50)68)60-47(74)39(26-30-27-58-32-14-7-6-13-31(30)32)65-43(70)35(17-10-23-57-49(53)54)61-46(73)38(25-29-11-4-3-5-12-29)64-45(72)37(63-44(36)71)20-24-77(2,75)76/h3-7,11-14,27,33-39,58H,8-10,15-26H2,1-2H3,(H2,50,68)(H,55,67)(H,59,66)(H,60,74)(H,61,73)(H,62,69)(H,63,71)(H,64,72)(H,65,70)(H4,51,52,56)(H4,53,54,57)/t33-,34-,35-,36-,37-,38+,39-/s2
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
8 -11.5n/an/an/an/an/a7.537



Palatin Technologies, Inc.

US Patent


Assay Description
A competitive inhibition binding assay is performed using membrane homogenates prepared from HEK-293 cells that express recombinant hMC4-R, hMC3-R, o...


US Patent US9458201 (2016)


BindingDB Entry DOI: 10.7270/Q2HT2N79
More data for this
Ligand-Target Pair