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BDBM135809 US8853227, TK- 000015

SMILES: Cc1cn2[C@@H]3O[C@H](CF)C(O)[C@@H]3Oc2nc1=O

InChI Key: InChIKey=QTKLHMLQXNPHTE-GWJYYXHLNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 135809   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Uridine phosphorylase (UPase)


(Homo sapiens (Human))
BDBM135809
PNG
(US8853227, TK- 000015)
Show SMILES Cc1cn2[C@@H]3O[C@H](CF)C(O)[C@@H]3Oc2nc1=O
Show InChI InChI=1/C10H11FN2O4/c1-4-3-13-9-7(6(14)5(2-11)16-9)17-10(13)12-8(4)15/h3,5-7,9,14H,2H2,1H3/t5-,6?,7+,9-/s2
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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a>1.00E+5n/an/an/an/a7.337



Tosk, Incorporated

US Patent


Assay Description
The aim of this study was to evaluate TK-112690 in vivo as an inhibitor of uridine phosphorylase (UPase) enzyme activity. The range of TK-112690 dose...


US Patent US8853227 (2014)


BindingDB Entry DOI: 10.7270/Q2D50KNM
More data for this
Ligand-Target Pair