BDBM136597 US10005783, 14::US10047097, 14::US10774085, Example 14::US11098046, Compound LOXO-101::US11267818, Example 14::US11453672, Example L-7::US8865698, 14::US9676783, 14

SMILES: O[C@H]1CCN(C1)C(=O)Nc1cnn2ccc(nc12)N1CCC[C@@H]1c1cc(F)ccc1F

InChI Key: InChIKey=NYNZQNWKBKUAII-UHFFFAOYSA-N

Data: 103 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 122 hits for monomerid = 136597   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
High affinity nerve growth factor receptor [441-796] (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.70	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.70	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.70	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.440	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.820	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.410	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.960	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.320	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.730	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.860	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.630	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.290	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	237	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NT-3 growth factor receptor (Human)	BDBM136597 (US8865698, 14 | US10047097, 14 | US9676783, 14 | U...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair