BDBM13709 1-({3-[2-(2,4-dichlorophenyl)ethoxy]-4-methoxyphenyl}carbonyl)-4-(pyridin-4-yl)piperazine::3-Oxybenzamide 95

SMILES: COc1ccc(cc1OCCc1ccc(Cl)cc1Cl)C(=O)N1CCN(CC1)c1ccncc1

InChI Key: InChIKey=GWDRNDFJJHXBAV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13709   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM13709 (1-({3-[2-(2,4-dichlorophenyl)ethoxy]-4-methoxyphen...) Show SMILES COc1ccc(cc1OCCc1ccc(Cl)cc1Cl)C(=O)N1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C25H25Cl2N3O3/c1-32-23-5-3-19(16-24(23)33-15-8-18-2-4-20(26)17-22(18)27)25(31)30-13-11-29(12-14-30)21-6-9-28-10-7-21/h2-7,9-10,16-17H,8,11-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Patents Similars	Article PubMed	5.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharma Deutschland GmbH					Assay Description The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...				J Med Chem 48: 3290-312 (2005) Article DOI: 10.1021/jm049187l BindingDB Entry DOI: 10.7270/Q28C9THZ
					More data for this Ligand-Target Pair