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BDBM13709 1-({3-[2-(2,4-dichlorophenyl)ethoxy]-4-methoxyphenyl}carbonyl)-4-(pyridin-4-yl)piperazine::3-Oxybenzamide 95

SMILES: COc1ccc(cc1OCCc1ccc(Cl)cc1Cl)C(=O)N1CCN(CC1)c1ccncc1

InChI Key: InChIKey=GWDRNDFJJHXBAV-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13709   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM13709
PNG
(1-({3-[2-(2,4-dichlorophenyl)ethoxy]-4-methoxyphen...)
Show SMILES COc1ccc(cc1OCCc1ccc(Cl)cc1Cl)C(=O)N1CCN(CC1)c1ccncc1
Show InChI InChI=1S/C25H25Cl2N3O3/c1-32-23-5-3-19(16-24(23)33-15-8-18-2-4-20(26)17-22(18)27)25(31)30-13-11-29(12-14-30)21-6-9-28-10-7-21/h2-7,9-10,16-17H,8,11-15H2,1H3
PDB
MMDB

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Similars

Article
PubMed
5.41E+3n/an/an/an/an/an/an/an/a



Aventis Pharma Deutschland GmbH



Assay Description
The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...


J Med Chem 48: 3290-312 (2005)


Article DOI: 10.1021/jm049187l
BindingDB Entry DOI: 10.7270/Q28C9THZ
More data for this
Ligand-Target Pair