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BDBM137272 US8871790, 352

SMILES: CC(C)CNC(=O)Nc1cc(ccc1C)C(=O)N1CCC2(CC1)OCc1cc(ccc21)C#N

InChI Key: InChIKey=XSGLHMQYVARERM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 137272   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty acid synthase


(Homo sapiens (Human))
BDBM137272
PNG
(US8871790, 352)
Show SMILES CC(C)CNC(=O)Nc1cc(ccc1C)C(=O)N1CCC2(CC1)OCc1cc(ccc21)C#N
Show InChI InChI=1S/C26H30N4O3/c1-17(2)15-28-25(32)29-23-13-20(6-4-18(23)3)24(31)30-10-8-26(9-11-30)22-7-5-19(14-27)12-21(22)16-33-26/h4-7,12-13,17H,8-11,15-16H2,1-3H3,(H2,28,29,32)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 880n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...


US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair