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BDBM137278 US8871790, 358

SMILES: Cc1ccc(cc1NC(=O)c1ccc(nc1)N1CCNCC1)C(=O)N1CCC2(CC1)OCc1cc(ccc21)C#N

InChI Key: InChIKey=UWHDXPCPBZDLFO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 137278   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty acid synthase


(Homo sapiens (Human))
BDBM137278
PNG
(US8871790, 358)
Show SMILES Cc1ccc(cc1NC(=O)c1ccc(nc1)N1CCNCC1)C(=O)N1CCC2(CC1)OCc1cc(ccc21)C#N
Show InChI InChI=1S/C31H32N6O3/c1-21-2-4-23(17-27(21)35-29(38)24-5-7-28(34-19-24)36-14-10-33-11-15-36)30(39)37-12-8-31(9-13-37)26-6-3-22(18-32)16-25(26)20-40-31/h2-7,16-17,19,33H,8-15,20H2,1H3,(H,35,38)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 805n/an/an/an/an/an/a



3-V Biosciences, Inc.

US Patent


Assay Description
The FASN enzyme was isolated from SKBr3 cells. SKBr3 is a human breast cancer cell-line with high levels of FASN expression. It is estimated that FAS...


US Patent US8871790 (2014)


BindingDB Entry DOI: 10.7270/Q2PG1QD3
More data for this
Ligand-Target Pair