Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits in this search

Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2) Mus musculus (mouse)	adamantane ether 10 ((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)	GoogleScholar KEGG UniProtKB/SwissProt	PC cid PC sid	PubMed	n/a	n/a	40000.0	n/a	n/a	7.2	22
Abbott Laboratories					Bioorg Med Chem Lett. 17: 750-5 (2007)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Mus musculus (mouse)	adamantane ether 10 ((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	3.0	n/a	n/a	7.2	22
Abbott Laboratories					Bioorg Med Chem Lett. 17: 750-5 (2007)
11-beta-Hydroxysteroid Dehydrogenase 2 (11-beta-HSD2) Homo sapiens (human)	adamantane ether 10 ((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)	DrugBank GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	12000.0	n/a	n/a	7.2	22
Abbott Laboratories					Bioorg Med Chem Lett. 17: 750-5 (2007)
11-beta-Hydroxysteroid Dehydrogenase 1 (11-beta-HSD1) Homo sapiens (human)	adamantane ether 10 ((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	6.0	n/a	n/a	7.2	22
Abbott Laboratories					Bioorg Med Chem Lett. 17: 750-5 (2007)