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BDBM137616 US8871934, 209

SMILES: CC(C)(C)C(=O)N1CCN(CC1)c1ccc2-c3ccccc3C(O)(c2c1)C(F)(F)F

InChI Key: InChIKey=LDPCGEGBHRAVPX-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 137616   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Pyruvate dehydrogenase kinase isoform 2 (PDHK2)


(Homo sapiens (Human))
BDBM137616
PNG
(US8871934, 209)
Show SMILES CC(C)(C)C(=O)N1CCN(CC1)c1ccc2-c3ccccc3C(O)(c2c1)C(F)(F)F
Show InChI InChI=1/C23H25F3N2O2/c1-21(2,3)20(29)28-12-10-27(11-13-28)15-8-9-17-16-6-4-5-7-18(16)22(30,19(17)14-15)23(24,25)26/h4-9,14,30H,10-13H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 281n/an/an/an/a8.030



Japan Tobacco Inc

US Patent


Assay Description
The inhibitory action of PDHK activity was indirectly evaluated by performing a kinase reaction in the presence of a test compound and measuring the ...


US Patent US8871934 (2014)


BindingDB Entry DOI: 10.7270/Q2JQ0ZQT
More data for this
Ligand-Target Pair