BindingDB logo
myBDB logout

BDBM138110 US8871934, 703

SMILES: OCC(CO)(CO)n1cc(cn1)-c1cc(F)cc2c1-c1ccccc1C2(O)C(F)(F)F

InChI Key: InChIKey=ZRBSKAJTTXBPBY-UHFFFAOYNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 138110   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Pyruvate dehydrogenase kinase


(Homo sapiens (Human))
BDBM138110
PNG
(US8871934, 703)
Show SMILES OCC(CO)(CO)n1cc(cn1)-c1cc(F)cc2c1-c1ccccc1C2(O)C(F)(F)F
Show InChI InChI=1/C21H18F4N2O4/c22-13-5-15(12-7-26-27(8-12)19(9-28,10-29)11-30)18-14-3-1-2-4-16(14)20(31,17(18)6-13)21(23,24)25/h1-8,28-31H,9-11H2
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 20n/an/an/an/a8.030



Japan Tobacco Inc

US Patent


Assay Description
The inhibitory action of PDHK activity was indirectly evaluated by performing a kinase reaction in the presence of a test compound and measuring the ...


US Patent US8871934 (2014)


BindingDB Entry DOI: 10.7270/Q2JQ0ZQT
More data for this
Ligand-Target Pair