BDBM138200 US8871778, 141

SMILES: Cc1nn(cc1CN1CC(O)C1)-c1ccnc(Nc2ccc3n(C)c(C)c(Cl)c3c2)n1

InChI Key: InChIKey=XHZDAKAAKUZJHY-UHFFFAOYSA-N

Data: 12 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 138200   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Human)	BDBM138200 (US8871778, 141) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	25
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Vascular endothelial growth factor receptor 2 (Human)	BDBM138200 (US8871778, 141) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	192	n/a	n/a	n/a	n/a	n/a	25
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Tyrosine-protein kinase SYK (Human)	BDBM138200 (US8871778, 141) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM138200 (US8871778, 141) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	25
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Tyrosine-protein kinase SYK (Human)	BDBM138200 (US8871778, 141) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM138200 (US8871778, 141) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ZAP-70 (Human)	BDBM138200 (US8871778, 141) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.39E+4	n/a	n/a	n/a	n/a	n/a	25
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Tyrosine-protein kinase JAK2 (Human)	BDBM138200 (US8871778, 141) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.12E+5	n/a	n/a	n/a	n/a	n/a	25
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Tyrosine-protein kinase JAK3 (Human)	BDBM138200 (US8871778, 141) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	25
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Aurora kinase B (Human)	BDBM138200 (US8871778, 141) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.71E+3	n/a	n/a	n/a	n/a	n/a	25
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Vascular endothelial growth factor receptor 2 (Human)	BDBM138200 (US8871778, 141) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	192	n/a	n/a	n/a	n/a	n/a	25
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Proto-oncogene tyrosine-protein kinase receptor Ret (Human)	BDBM138200 (US8871778, 141) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	25
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