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BDBM139334 US8614223, 120

SMILES: COc1cccc(c1)C1(CC1)Nc1ncc(cn1)C(=O)NO

InChI Key: InChIKey=HACIRUZXPBRMTD-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 139334   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase 1


(Homo sapiens (Human))
BDBM139334
PNG
(US8614223, 120)
Show SMILES COc1cccc(c1)C1(CC1)Nc1ncc(cn1)C(=O)NO
Show InChI InChI=1S/C15H16N4O3/c1-22-12-4-2-3-11(7-12)15(5-6-15)18-14-16-8-10(9-17-14)13(20)19-21/h2-4,7-9,21H,5-6H2,1H3,(H,19,20)(H,16,17,18)
PDB
MMDB

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UniProtKB/TrEMBL

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PC cid
PC sid
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Similars

US Patent
n/an/a 38n/an/an/an/a7.425



Acetylon Pharmaceuticals Inc

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))
BDBM139334
PNG
(US8614223, 120)
Show SMILES COc1cccc(c1)C1(CC1)Nc1ncc(cn1)C(=O)NO
Show InChI InChI=1S/C15H16N4O3/c1-22-12-4-2-3-11(7-12)15(5-6-15)18-14-16-8-10(9-17-14)13(20)19-21/h2-4,7-9,21H,5-6H2,1H3,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 4n/an/an/an/a7.425



Acetylon Pharmaceuticals Inc

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase 3


(Homo sapiens (Human))
BDBM139334
PNG
(US8614223, 120)
Show SMILES COc1cccc(c1)C1(CC1)Nc1ncc(cn1)C(=O)NO
Show InChI InChI=1S/C15H16N4O3/c1-22-12-4-2-3-11(7-12)15(5-6-15)18-14-16-8-10(9-17-14)13(20)19-21/h2-4,7-9,21H,5-6H2,1H3,(H,19,20)(H,16,17,18)
PDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 128n/an/an/an/a7.425



Acetylon Pharmaceuticals Inc

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair
Histone deacetylase 2


(Homo sapiens (Human))
BDBM139334
PNG
(US8614223, 120)
Show SMILES COc1cccc(c1)C1(CC1)Nc1ncc(cn1)C(=O)NO
Show InChI InChI=1S/C15H16N4O3/c1-22-12-4-2-3-11(7-12)15(5-6-15)18-14-16-8-10(9-17-14)13(20)19-21/h2-4,7-9,21H,5-6H2,1H3,(H,19,20)(H,16,17,18)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 53n/an/an/an/a7.425



Acetylon Pharmaceuticals Inc

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8614223 (2013)


BindingDB Entry DOI: 10.7270/Q2B27T00
More data for this
Ligand-Target Pair