BDBM13990 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-(methoxycarbonyl)phenoxy]prop-1-en-1-yl]phenyl}-1,2-oxazole-3-carboxylic acid::CHEMBL117869::Isoxazole carboxylic acid analog 1

SMILES: COC(=O)c1c(O)cccc1OC\C=C\c1ccc(F)c(c1)-c1cc(no1)C(O)=O

InChI Key: InChIKey=QKHWJUMLYAYZFS-UHFFFAOYSA-N

Data: 13 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 13990   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM13990 (CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM13990 (CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Human)	BDBM13990 (CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.64E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM13990 (CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM13990 (CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 [1-298] (Human)	BDBM13990 (CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		6.90E+3	-6.97	n/a	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM13990 (CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM13990 (CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM13990 (CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM13990 (CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM13990 (CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		6.92E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM13990 (CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Human)	BDBM13990 (CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.64E+5	-5.11	n/a	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Human)	BDBM13990 (CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.64E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Human)	BDBM13990 (CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.64E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 2 (Human)	BDBM13990 (CHEMBL117869 | 5-{2-fluoro-5-[(1E)-3-[3-hydroxy-2-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.64E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair