BDBM140010 US8901310, Example 2

SMILES Cc1ncccc1NC(=O)c1ccc2c(CC[C@@H]3C[C@@](CC[C@@]23Cc2ccccc2)(OP(O)(O)=O)C(F)(F)F)c1

InChI Key InChIKey=BVXLAHSJXXSWFF-KEKPKEOLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 140010   

TargetInterleukin-6(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140010(US8901310, Example 2)
Affinity DataIC50:  60nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140010(US8901310, Example 2)
Affinity DataIC50:  42nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140010(US8901310, Example 2)
Affinity DataIC50:  79nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
In DepthDetails US Patent