BDBM140012 US8901310, Comparator B

SMILES Cc1cnc(NC(=O)c2ccc3c(CC[C@@H]4C[C@](O)(CC[C@@]34Cc3ccccc3)C(F)(F)F)c2)c(C)n1

InChI Key InChIKey=VLRUOHNPKMZQHN-KEKPKEOLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 140012   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140012(US8901310, Comparator B)
Affinity DataIC50:  0.350nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-6(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM140012(US8901310, Comparator B)
Affinity DataIC50:  4nMAssay Description:The glucocorticoid receptor fluorescence polarization ligand binding (GRFP) assay is used to evaluate direct binding of testing compounds to full-len...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent