BDBM140116 US8901315, 228

SMILES: CN1CCN(CCNC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)C(=O)C1=O

InChI Key: InChIKey=XIGCQRXKJLXWQF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 140116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (PDE4) (Mus musculus (Mouse))	BDBM140116 (US8901315, 228) Show SMILES CN1CCN(CCNC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)C(=O)C1=O Show InChI InChI=1S/C20H27N5O3S/c1-13-15-12-16(29-20(15)25(22-13)14-6-4-3-5-7-14)17(26)21-8-9-24-11-10-23(2)18(27)19(24)28/h12,14H,3-11H2,1-2H3,(H,21,26)	PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	6.5	4
Daiichi Sankyo Company, Limited US Patent					Assay Description The PDE 4 (phosphodiesterase IV) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifie...				US Patent US8901315 (2014) BindingDB Entry DOI: 10.7270/Q2GM860P
					More data for this Ligand-Target Pair
Phosphodiesterase 7 (Homo sapiens (Human))	BDBM140116 (US8901315, 228) Show SMILES CN1CCN(CCNC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)C(=O)C1=O Show InChI InChI=1S/C20H27N5O3S/c1-13-15-12-16(29-20(15)25(22-13)14-6-4-3-5-7-14)17(26)21-8-9-24-11-10-23(2)18(27)19(24)28/h12,14H,3-11H2,1-2H3,(H,21,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	7.5	4
Daiichi Sankyo Company, Limited US Patent					Assay Description The PDE 7 (phosphodiesterase VII) inhibiting effect of the compounds of the present invention was performed by the following method, which was modifi...				US Patent US8901315 (2014) BindingDB Entry DOI: 10.7270/Q2GM860P
					More data for this Ligand-Target Pair