BDBM14029 (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE::4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-1-carboxamide::US10183931, Y-27632::Y-27632

SMILES: C[C@@H](N)[C@H]1CC[C@@H](CC1)C(=O)Nc1ccncc1

InChI Key: InChIKey=IYOZTVGMEWJPKR-UHFFFAOYSA-N

Data: 20 KI  39 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 59 hits for monomerid = 14029   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Rat)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	335	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Myotonin-protein kinase (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase N2 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cell division control protein 42 homolog (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-5 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase N2 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase N2 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	871	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	245	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
C-C motif chemokine 2 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha [E127D] (Bovine)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha [L49I,T183A] (Bovine)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha [Q181K,T183A] (Bovine)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha [V123M,T183A] (Bovine)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha [L49I,Q181K,T183A] (Bovine)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha [V123M,Q181K,T183A] (Bovine)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha [L49I,V123M,Q181K,T183A] (Bovine)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha [L49I,V123M,E127D,Q181K,T183A] (Bovine)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Bovine)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha [T183A] (Bovine)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha [V123M] (Bovine)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	6.8	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha [L49I] (Bovine)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	6.8	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha (Bovine)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	6.8	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		25.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		150	-9.46	n/a	n/a	n/a	n/a	n/a	7.6	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM14029 (4-[(1R)-1-aminoethyl]-N-(pyridin-4-yl)cyclohexane-...) Show SMILES Show InChI	GoogleScholar	UniChem		220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair