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BDBM14055 N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(trifluoromethyl)phenyl]-1,4,5,6-tetrahydropyridine-3-carboxamide::dihydropyridone indazole amide 15
SMILES: CC1=C(C(CC(=O)N1)c1ccc(cc1)C(F)(F)F)C(=O)Nc1cc2cn[nH]c2cc1F
InChI Key: InChIKey=OLIIUAHHAZEXEX-UHFFFAOYSA-N
Data: 1 IC50
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Rho-associated protein kinase 1 (Human) | BDBM14055![]() (N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(...) | GoogleScholar | UniChem | n/a | n/a | 14 | n/a | n/a | n/a | n/a | 7.4 | 22 | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Leucine-rich repeat serine/threonine-protein kinase 2 (Human) | BDBM14055![]() (N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(...) | GoogleScholar | UniChem | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Leucine-rich repeat serine/threonine-protein kinase 2 (Human) | BDBM14055![]() (N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(...) | GoogleScholar | UniChem | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Rho-associated protein kinase 2 (Human) | BDBM14055![]() (N-(6-fluoro-1H-indazol-5-yl)-2-methyl-6-oxo-4-[4-(...) | GoogleScholar | UniChem | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||