BDBM14061 8,9-Dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine::CHEMBL38681::LY134046::tetrahydrobenzazepine (THBA) deriv.

SMILES: c1cc(c(c2c1CCCNC2)Cl)Cl

InChI Key: InChIKey=IADAQXMUWITWNG-UHFFFAOYSA-N

Data: 11 KI

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 14061   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phenylethanolamine N-methyltransferase (Human)	BDBM14061 (8,9-Dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine |...) Show SMILES Show InChI	GoogleScholar	UniChem		10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Bovine)	BDBM14061 (8,9-Dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine |...) Show SMILES Show InChI	GoogleScholar	UniChem		220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Bovine)	BDBM14061 (8,9-Dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine |...) Show SMILES Show InChI	GoogleScholar	UniChem		260	-9.34	n/a	n/a	n/a	n/a	n/a	8.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Bovine)	BDBM14061 (8,9-Dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine |...) Show SMILES Show InChI	GoogleScholar	UniChem		260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Bovine)	BDBM14061 (8,9-Dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine |...) Show SMILES Show InChI	GoogleScholar	UniChem		260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Bovine)	BDBM14061 (8,9-Dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine |...) Show SMILES Show InChI	GoogleScholar	UniChem		260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Human)	BDBM14061 (8,9-Dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine |...) Show SMILES Show InChI	GoogleScholar	UniChem		280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Bovine)	BDBM14061 (8,9-Dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine |...) Show SMILES Show InChI	GoogleScholar	UniChem		1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phenylethanolamine N-methyltransferase (Human)	BDBM14061 (8,9-Dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine |...) Show SMILES Show InChI	GoogleScholar	UniChem		4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465] (Rat)	BDBM14061 (8,9-Dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine |...) Show SMILES Show InChI	GoogleScholar	UniChem		4.50E+3	-7.29	n/a	n/a	n/a	n/a	n/a	7.7	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (Rat)	BDBM14061 (8,9-Dichloro-2,3,4,5-tetrahydro-1H-2-benzazepine |...) Show SMILES Show InChI	GoogleScholar	UniChem		4.56E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair