BDBM141126 US8653100, 160::US8653100, 164::US8653100, 192::US8653100, 193::US8653100, 61

SMILES Clc1ccc(cc1)C1(CCC1)C1NCCc2ccc(OCCNS(=O)(=O)C3CCCNC3)cc12

InChI Key InChIKey=ODFQJLPCXCOLLD-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 141126   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM141126(US8653100, 160 | US8653100, 164 | US8653100, 192 |...)
Affinity DataKi: <100nMpH: 7.5Assay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM141126(US8653100, 160 | US8653100, 164 | US8653100, 192 |...)
Affinity DataKi: <1.00E+3nMpH: 7.5Assay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM141126(US8653100, 160 | US8653100, 164 | US8653100, 192 |...)
Affinity DataKi: <1.00E+4nMpH: 7.5Assay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM141126(US8653100, 160 | US8653100, 164 | US8653100, 192 |...)
Affinity DataKi: <1.00E+4nMpH: 7.5Assay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM141126(US8653100, 160 | US8653100, 164 | US8653100, 192 |...)
Affinity DataIC50: <100nMAssay Description:[3H]-Glycine uptake into recombinant CHO cells expressing human GlyT1: Human GlyT1c expressing recombinant hGlyT1c_5_CHO cells were plated at 20,000 ...More data for this Ligand-Target Pair
In DepthDetails US Patent