BDBM141403 US10668051, Compound Example 33::US8921364, 33

SMILES Fc1cccc(F)c1C(=O)Nc1ccc(c(F)c1)-n1nc(cc1C1CC1)C1CC1

InChI Key InChIKey=FQBXOFLHBKDTPO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 141403   

TargetCalcium release-activated calcium channel protein 1(Homo sapiens (Human))
Rhizen Pharmaceuticals

US Patent
LigandPNGBDBM141403(US10668051, Compound Example 33 | US8921364, 33)
Affinity DataIC50:  145nMAssay Description:Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat #T9033) induced endoplasmic calcium release in Jurkat cells, (see Yasur...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEF-hand calcium-binding domain-containing protein 4B(Homo sapiens (Human))
Rhizen Pharmaceuticals

US Patent
LigandPNGBDBM141403(US10668051, Compound Example 33 | US8921364, 33)
Affinity DataIC50:  145nMT: 2°CAssay Description:Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat # T9033) induced endoplasmic calcium release in Jurkat cells. (see Yasu...More data for this Ligand-Target Pair
In DepthDetails US Patent