BDBM142019 US10435361, Example 16::US8927563, I::US9481648, 16::US9790174, Example 16

SMILES: COCCOCCOCCNC(=O)c1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(cc(NS(C)(=O)=O)c4OC)C(C)(C)C)c4ccccc34)n2)cc(c1)C#C

InChI Key: InChIKey=FWXVGKSWZJEPQI-UHFFFAOYSA-N

Data: 17 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 142019   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Human)	BDBM142019 (US8927563, I | US9481648, 16 | US9790174, Example ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	224	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM142019 (US8927563, I | US9481648, 16 | US9790174, Example ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM142019 (US8927563, I | US9481648, 16 | US9790174, Example ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM142019 (US8927563, I | US9481648, 16 | US9790174, Example ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM142019 (US8927563, I | US9481648, 16 | US9790174, Example ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM142019 (US8927563, I | US9481648, 16 | US9790174, Example ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 alpha (Human)	BDBM142019 (US8927563, I | US9481648, 16 | US9790174, Example ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	411	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase SYK (Human)	BDBM142019 (US8927563, I | US9481648, 16 | US9790174, Example ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	591	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM142019 (US8927563, I | US9481648, 16 | US9790174, Example ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM142019 (US8927563, I | US9481648, 16 | US9790174, Example ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	224	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Human)	BDBM142019 (US8927563, I | US9481648, 16 | US9790174, Example ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	411	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM142019 (US8927563, I | US9481648, 16 | US9790174, Example ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	591	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM142019 (US8927563, I | US9481648, 16 | US9790174, Example ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 12 (Human)	BDBM142019 (US8927563, I | US9481648, 16 | US9790174, Example ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	224	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 alpha (Human)	BDBM142019 (US8927563, I | US9481648, 16 | US9790174, Example ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	411	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Human)	BDBM142019 (US8927563, I | US9481648, 16 | US9790174, Example ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	591	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM142019 (US8927563, I | US9481648, 16 | US9790174, Example ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair