BindingDB logo
myBDB logout

BDBM142173 US8933079, 4.12

SMILES: Cc1cc(CN2CCC[C@@H](O)C2)ccc1C(=O)Cn1ccc(OCc2ccc(Br)cn2)cc1=O

InChI Key: InChIKey=REBAQHOYUXITBK-ANBDAQEENA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142173   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM142173
PNG
(US8933079, 4.12)
Show SMILES Cc1cc(CN2CCC[C@@H](O)C2)ccc1C(=O)Cn1ccc(OCc2ccc(Br)cn2)cc1=O
Show InChI InChI=1/C26H28BrN3O4/c1-18-11-19(14-29-9-2-3-22(31)15-29)4-7-24(18)25(32)16-30-10-8-23(12-26(30)33)34-17-21-6-5-20(27)13-28-21/h4-8,10-13,22,31H,2-3,9,14-17H2,1H3/t22-/s2
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 23n/an/an/an/a7.0n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Membranes from CHO/Galpha16 cells stably transfected with human hMCH-1R are resuspended using a syringe (needle 0.6x25 mm) and diluted in test buffer...


US Patent US8933079 (2015)


BindingDB Entry DOI: 10.7270/Q2P26WVR
More data for this
Ligand-Target Pair