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BDBM142218 US8933079, 8.4

SMILES: Cc1cc(CN2CCC[C@H](O)C2)ccc1C(=O)Cn1ncc(OCc2ccc(Br)cn2)cc1=O

InChI Key: InChIKey=ZAKDVFBDUQBXAD-RNZRUAGMNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142218   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))
BDBM142218
PNG
(US8933079, 8.4)
Show SMILES Cc1cc(CN2CCC[C@H](O)C2)ccc1C(=O)Cn1ncc(OCc2ccc(Br)cn2)cc1=O
Show InChI InChI=1/C25H27BrN4O4/c1-17-9-18(13-29-8-2-3-21(31)14-29)4-7-23(17)24(32)15-30-25(33)10-22(12-28-30)34-16-20-6-5-19(26)11-27-20/h4-7,9-12,21,31H,2-3,8,13-16H2,1H3/t21-/s2
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Similars

US Patent
n/an/a 24n/an/an/an/a7.0n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Membranes from CHO/Galpha16 cells stably transfected with human hMCH-1R are resuspended using a syringe (needle 0.6x25 mm) and diluted in test buffer...


US Patent US8933079 (2015)


BindingDB Entry DOI: 10.7270/Q2P26WVR
More data for this
Ligand-Target Pair