BDBM142256 US8933099, 22::US9951047, Compound (I)
SMILES: CNC(=O)n1ccc2c1cc(c(c2)Oc3ccnc(c3)NC(=O)c4ccc(cc4)C5CCN(CC5)CCO)OCCOC
InChI Key: InChIKey=IBHOLSBDZMIPPT-UHFFFAOYSA-N
Data: 8 IC50
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 142256 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Fibroblast growth factor receptor 1
(Human) | BDBM142256
 (US8933099, 22 | US9951047, Compound (I)) | GoogleScholar
| UniChem
| | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | 25 |
TBA
| |
Citation and Details
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More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 2
(Human) | BDBM142256
 (US8933099, 22 | US9951047, Compound (I)) | GoogleScholar
| UniChem
| | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a | 25 |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 3
(Human) | BDBM142256
 (US8933099, 22 | US9951047, Compound (I)) | GoogleScholar
| UniChem
| | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | 25 |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 4
(Human) | BDBM142256
 (US8933099, 22 | US9951047, Compound (I)) | GoogleScholar
| UniChem
| | n/a | n/a | 683 | n/a | n/a | n/a | n/a | n/a | 25 |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 1
(Human) | BDBM142256
 (US8933099, 22 | US9951047, Compound (I)) | GoogleScholar
| UniChem
| | n/a | n/a | 5.80 | n/a | n/a | n/a | n/a | n/a | 25 |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Fibroblast growth factor 2
(Human) | BDBM142256
 (US8933099, 22 | US9951047, Compound (I)) | GoogleScholar
| UniChem
| | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | 25 |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 3
(Human) | BDBM142256
 (US8933099, 22 | US9951047, Compound (I)) | GoogleScholar
| UniChem
| | n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | 25 |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Fibroblast growth factor receptor 4
(Human) | BDBM142256
 (US8933099, 22 | US9951047, Compound (I)) | GoogleScholar
| UniChem
| | n/a | n/a | 645 | n/a | n/a | n/a | n/a | n/a | 25 |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |