BDBM14239 5-(carboxymethoxy)-10-{[1-(phenylmethane)sulfonylpiperidin-4-yl]amino}-3,7-dithiatricyclo[6.4.0.0^{2,6}]dodeca-1(8),2(6),4,9,11-pentaene-4-carboxylic acid::thienobenzothiophene 29

SMILES OC(=O)COc1c(sc2c1sc1cc(NC3CCN(CC3)S(=O)(=O)Cc3ccccc3)ccc21)C(O)=O

InChI Key InChIKey=UEELPALQXUYKFT-UHFFFAOYSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14239   

TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM14239(5-(carboxymethoxy)-10-{[1-(phenylmethane)sulfonylp...)
Affinity DataKi:  370nM ΔG°:  -8.77kcal/moleT: 2°CAssay Description:The enzymatic assay was carried out at room temperature in 96-well plates. The initial rate of PTPase-catalyzed hydrolysis of p-nitrophenol phosphate...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM14239(5-(carboxymethoxy)-10-{[1-(phenylmethane)sulfonylp...)
Affinity DataKi:  380nM ΔG°:  -8.75kcal/moleT: 2°CAssay Description:The enzymatic assay was carried out at room temperature in 96-well plates. The initial rate of PTPase-catalyzed hydrolysis of p-nitrophenol phosphate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed