BDBM14252 4-bromo-3-(carboxymethoxy)-5-(3-hydroxyphenyl)thiophene-2-carboxylic acid::CHEMBL213662::Monocyclic thiophene analog 19

SMILES OC(=O)COc1c(Br)c(sc1C(O)=O)-c1cccc(O)c1

InChI Key InChIKey=ISKXZFZNQIPKOR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14252   

TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM14252(4-bromo-3-(carboxymethoxy)-5-(3-hydroxyphenyl)thio...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human recombinant PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM14252(4-bromo-3-(carboxymethoxy)-5-(3-hydroxyphenyl)thio...)
Affinity DataKi:  1.00E+3nM ΔG°:  -8.10kcal/molepH: 7.0 T: 2°CAssay Description:The enzymatic assay was carried out at room temperature in 96-well plates. The initial rate of PTPase-catalyzed hydrolysis of p-nitrophenol phosphate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed