BDBM14262 4-bromo-3-(carboxymethoxy)-5-(4-{[4-(trifluoromethyl)benzene]sulfonamido}phenyl)thiophene-2-carboxylic acid::Monocyclic thiophene analog 31

SMILES OC(=O)COc1c(Br)c(sc1C(O)=O)-c1ccc(NS(=O)(=O)c2ccc(cc2)C(F)(F)F)cc1

InChI Key InChIKey=UUTGESRRJSEYNX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14262   

TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM14262(4-bromo-3-(carboxymethoxy)-5-(4-{[4-(trifluorometh...)
Affinity DataKi:  200nM ΔG°:  -9.13kcal/moleT: 2°CAssay Description:The enzymatic assay was carried out at room temperature in 96-well plates. The initial rate of PTPase-catalyzed hydrolysis of p-nitrophenol phosphate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed