BDBM14320 1-amino-isoquinoline::CHEMBL62083::Fragment 17::fragment 1 (J. med. chem.,50,1116)::isoquinolin-1-amine

SMILES: c1ccc2c(c1)ccnc2N

InChI Key: InChIKey=OSILBMSORKFRTB-UHFFFAOYSA-N

Data: 5 KI  4 IC50  2 Kd  1 Other

PDB links: 8 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 14320   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Human)	BDBM14320 (CHEMBL62083 | 1-amino-isoquinoline | fragment 1 (J...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	n/a	5.0	22
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Neutrophil cytosol factor 1 (Human)	BDBM14320 (CHEMBL62083 | 1-amino-isoquinoline | fragment 1 (J...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.87E+5	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, brain (Human)	BDBM14320 (CHEMBL62083 | 1-amino-isoquinoline | fragment 1 (J...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, inducible (Human)	BDBM14320 (CHEMBL62083 | 1-amino-isoquinoline | fragment 1 (J...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, endothelial (Human)	BDBM14320 (CHEMBL62083 | 1-amino-isoquinoline | fragment 1 (J...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase (Mouse)	BDBM14320 (CHEMBL62083 | 1-amino-isoquinoline | fragment 1 (J...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.50E+5	n/a	n/a	n/a	n/a	n/a
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Coagulation factor XII (Human)	BDBM14320 (CHEMBL62083 | 1-amino-isoquinoline | fragment 1 (J...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Human)	BDBM14320 (CHEMBL62083 | 1-amino-isoquinoline | fragment 1 (J...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Urokinase-type plasminogen activator (Human)	BDBM14320 (CHEMBL62083 | 1-amino-isoquinoline | fragment 1 (J...) Show SMILES Show InChI	GoogleScholar	UniChem		5.01E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tryptase beta-2 (Human)	BDBM14320 (CHEMBL62083 | 1-amino-isoquinoline | fragment 1 (J...) Show SMILES Show InChI	GoogleScholar	UniChem		3.90E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Neutrophil cytosol factor 1 (Human)	BDBM14320 (CHEMBL62083 | 1-amino-isoquinoline | fragment 1 (J...) Show SMILES Show InChI	GoogleScholar	UniChem		5.94E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine protease 1 (Bovine)	BDBM14320 (CHEMBL62083 | 1-amino-isoquinoline | fragment 1 (J...) Show SMILES Show InChI	GoogleScholar	UniChem		6.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Coagulation factor VII/Tissue factor (Human)	BDBM14320 (CHEMBL62083 | 1-amino-isoquinoline | fragment 1 (J...) Show SMILES Show InChI	GoogleScholar	UniChem		4.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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