BDBM14322 2-Aminoquinoline 1::2-aminoquinoline::CHEMBL61236::Fragment 19::Quinolin-2-amine::fragment 2 (J. med. chem.,50,1116)

SMILES: c1ccc2c(c1)ccc(n2)N

InChI Key: InChIKey=GCMNJUJAKQGROZ-UHFFFAOYSA-N

Data: 5 KI  5 IC50  5 Kd  3 EC50  1 Other

PDB links: 5 PDB IDs match this monomer.

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 14322   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Human)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.00E+5	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Human)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+6	n/a	n/a	n/a	n/a	5.0	22
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Beta-secretase 1 (Human)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	n/a	n/a	n/a	5.0	22
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Nitric oxide synthase oxygenase [E25A,E26A,E316A] (Bacillus subtilis)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase oxygenase [E25A,E26A,I218V,E316A] (Bacillus subtilis)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Human)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Neutrophil cytosol factor 1 (Human)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.88E+5	n/a	n/a	n/a	n/a	n/a
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Nitric oxide synthase, inducible (Human)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cytoplasmic protein NCK1 (Human)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase (Mouse)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.25E+5	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase HCK (Human)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase (Mouse)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.60E+5	n/a	n/a	n/a	n/a
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Neutrophil cytosol factor 1 (Human)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.43E+5	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Human)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.00E+5	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 3A (Rat)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serotonin 2 (5-HT2) receptor (Rat)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tryptase beta-2 (Human)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		2.20E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Neutrophil cytosol factor 1 (Human)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		4.28E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine protease 1 (Bovine)	BDBM14322 (CHEMBL61236 | 2-aminoquinoline | fragment 2 (J. me...) Show SMILES Show InChI	GoogleScholar	UniChem		5.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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