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BDBM14323 Fragment 20::quinazoline-2,4-diamine

SMILES: c1ccc2c(c1)c(nc(n2)N)N

InChI Key: InChIKey=XELRMPRLCPFTBH-UHFFFAOYSA-N

Data: 2 KI 2 IC50

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 14323
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dihydrofolate reductase (Rat)	BDBM14323 (quinazoline-2,4-diamine \| Fragment 20) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
m7GpppX diphosphatase (Human)	BDBM14323 (quinazoline-2,4-diamine \| Fragment 20) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tryptase beta-2 (Human)	BDBM14323 (quinazoline-2,4-diamine \| Fragment 20) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Serine protease 1 (Bovine)	BDBM14323 (quinazoline-2,4-diamine \| Fragment 20) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair