BDBM14363 3-(2-propoxyphenyl)-2,4,7,8,9-pentazabicyclo[4.3.0]nona-1,3,6-trien-5-one::5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one::Tocris-0947::Zaprinast

SMILES: CCCOc1ccccc1-c1nc2nn[nH]c2c(=O)[nH]1

InChI Key: InChIKey=REZGGXNDEMKIQB-UHFFFAOYSA-N

Data: 11 KI  43 IC50  21 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 75 hits for monomerid = 14363   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase (Pig)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bovine)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphodiesterase (Bovine)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
3',5'-cyclic-AMP phosphodiesterase (Pig)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bovine)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Rat)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.68E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
3',5'-cyclic-AMP phosphodiesterase (Pig)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.96E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphodiesterase (Pig)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alkaline phosphatase, tissue-nonspecific isozyme (Rat)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.75E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.96E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Mouse)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	980	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G protein-coupled receptor GPR35 (Rat)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	61	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.24E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alkaline phosphatase, germ cell type (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.25E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Rat)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	340	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.52E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	160	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
G-protein coupled receptor 35 (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Rat)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphodiesterase (Bovine)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.22E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Human)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bovine)	BDBM14363 (5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair