BDBM1437 5-methoxyindole-2-carboxylic acid [N -[3-(aminoethyl)pyridin-2-yl]piperazide]::BHAP deriv.::CHEMBL280527::CHEMBL7264::N-ethyl-2-{4-[(5-methoxy-1H-indol-2-yl)carbonyl]piperazin-1-yl}pyridin-3-amine::U-87201E::bis(heteroaryl)piperazine analog

SMILES: CCNc1cccnc1N1CCN(CC1)C(=O)c1cc2cc(OC)ccc2[nH]1

InChI Key: InChIKey=UCPOMLWZWRTIAA-UHFFFAOYSA-N

Data: 11 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 1437   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM1437 (BHAP deriv. | CHEMBL7264 | N-ethyl-2-{4-[(5-methox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
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Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM1437 (BHAP deriv. | CHEMBL7264 | N-ethyl-2-{4-[(5-methox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	8.3	28
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Gag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L] (Human immunodeficiency virus type 1)	BDBM1437 (BHAP deriv. | CHEMBL7264 | N-ethyl-2-{4-[(5-methox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Gag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C] (Human immunodeficiency virus type 1)	BDBM1437 (BHAP deriv. | CHEMBL7264 | N-ethyl-2-{4-[(5-methox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM1437 (BHAP deriv. | CHEMBL7264 | N-ethyl-2-{4-[(5-methox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	8.2	n/a
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Gag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N] (Human immunodeficiency virus type 1)	BDBM1437 (BHAP deriv. | CHEMBL7264 | N-ethyl-2-{4-[(5-methox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.34E+4	n/a	n/a	n/a	n/a	8.2	n/a
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Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM1437 (BHAP deriv. | CHEMBL7264 | N-ethyl-2-{4-[(5-methox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	8.3	37
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Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM1437 (BHAP deriv. | CHEMBL7264 | N-ethyl-2-{4-[(5-methox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM1437 (BHAP deriv. | CHEMBL7264 | N-ethyl-2-{4-[(5-methox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Reverse transcriptase (Human immunodeficiency virus type 1)	BDBM1437 (BHAP deriv. | CHEMBL7264 | N-ethyl-2-{4-[(5-methox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM1437 (BHAP deriv. | CHEMBL7264 | N-ethyl-2-{4-[(5-methox...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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