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BDBM143861 US8969325, 62

SMILES: CC1(C)C[C@@H](NC(=O)Nc2ccc3CN(CCO)C(=O)Nc3c2)c2ccc(nc2O1)C(F)(F)F

InChI Key: InChIKey=LUODBZIJTPRQNX-MRXNPFEDSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 143861   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM143861
PNG
(US8969325, 62)
Show SMILES CC1(C)C[C@@H](NC(=O)Nc2ccc3CN(CCO)C(=O)Nc3c2)c2ccc(nc2O1)C(F)(F)F
Show InChI InChI=1S/C22H24F3N5O4/c1-21(2)10-16(14-5-6-17(22(23,24)25)29-18(14)34-21)27-19(32)26-13-4-3-12-11-30(7-8-31)20(33)28-15(12)9-13/h3-6,9,16,31H,7-8,10-11H2,1-2H3,(H,28,33)(H2,26,27,32)/t16-/m1/s1
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Similars

US Patent
n/an/a 1.50E+3n/an/an/an/an/an/a



AbbVie Inc

US Patent


Assay Description
The cDNA for human TRPV1 (hTRPV1) was isolated by reverse transcriptase-polymerase chain reaction (RT-PCR) from human small intestine poly A+ RNA sup...


US Patent US8969325 (2015)


BindingDB Entry DOI: 10.7270/Q29P30BX
More data for this
Ligand-Target Pair