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BDBM144259 US8952008, 15

SMILES: CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1F)S(=O)(=O)CC

InChI Key: InChIKey=WAMORTISASPDPO-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144259   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
GABA A receptor alpha-2/beta-2/gamma-2


(Homo sapiens (Human))
BDBM144259
PNG
(US8952008, 15)
Show SMILES CCn1cnc2c(cnnc12)-c1ccc(F)c(c1)-c1ccc(cc1F)S(=O)(=O)CC
Show InChI InChI=1S/C21H18F2N4O2S/c1-3-27-12-24-20-17(11-25-26-21(20)27)13-5-8-18(22)16(9-13)15-7-6-14(10-19(15)23)30(28,29)4-2/h5-12H,3-4H2,1-2H3
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
18.2n/an/an/an/an/an/an/an/a



Pfizer Inc

US Patent


Assay Description
The affinity of the test compounds was determined by radioligand competition binding assay, using the known compound [3H]Ro-15-1788 (Flumazenil) (Per...


US Patent US8952008 (2015)


BindingDB Entry DOI: 10.7270/Q2XD10DW
More data for this
Ligand-Target Pair