BDBM144321 US8969336, 565

SMILES CCc1nc(C(N)=O)c(Nc2ccc(cc2)N2CCN(C)CC2)nc1N[C@H]1CC[C@H](O)CC1

InChI Key InChIKey=LVUGQRCDFBJDSM-UAPYVXQJSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 144321   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Astellas Pharma

US Patent
LigandPNGBDBM144321(US8969336, 565)
Affinity DataIC50:  1.10nMAssay Description:A partial protein of only a kinase domain of RET protein was purchased from Carna Biosciences Inc., Japan. The phosphorylation activity toward a pept...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astellas Pharma

US Patent
LigandPNGBDBM144321(US8969336, 565)
Affinity DataIC50:  0.440nMAssay Description:A partial protein of only a kinase domain of FLT3 protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Examp...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Astellas Pharma

US Patent
LigandPNGBDBM144321(US8969336, 565)
Affinity DataIC50:  0.400nMAssay Description:A partial protein of only a kinase domain of ROS protein was purchased from Carna Biosciences Inc., Japan, and tests were conducted as in Test Exampl...More data for this Ligand-Target Pair
In DepthDetails US Patent