BDBM144347 US8969348, {4-[(1,4-Dimethyl-1H-indol-3-yl)methyl]-1-oxophthalazin-2(1H)-yl}(phenyl)acetic acid

SMILES Cc1cccc2n(C)cc(Cc3nn(C(C(O)=O)c4ccccc4)c(=O)c4ccccc34)c12

InChI Key InChIKey=UAYYAAIBVQDTIU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144347   

TargetChymase(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM144347(US8969348, {4-[(1,4-Dimethyl-1H-indol-3-yl)methyl]...)
Affinity DataIC50:  7nMpH: 8.0Assay Description:Chymase assays were performed in a total volume of 15 uL in Corning black opaque 384-well microtiter plates with a non-binding surface (Corning, N.Y....More data for this Ligand-Target Pair
In DepthDetails US Patent