BDBM14460 (-)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5Hbenzo[5,6]-cyclohepta[1,2-b]pyridin-11(S)-yl)-1-piperidinyl]-2-oxo-ethyl]-1-piperidinecarboxamide::4-(2-{4-[(2S)-6,15-dibromo-13-chloro-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-2-yl]piperidin-1-yl}-2-oxoethyl)piperidine-1-carboxamide::CHEMBL67405::SCH 66336 analog::Trihalobenzocycloheptapyridine Tricyclic Compound 16

SMILES: NC(=O)N1CCC(CC(=O)N2CCC(CC2)[C@@H]2c3ncc(Br)cc3CCc3cc(Cl)cc(Br)c23)CC1

InChI Key: InChIKey=DHMTURDWPRKSOA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14460   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Human)	BDBM14460 (4-(2-{4-[(2S)-6,15-dibromo-13-chloro-4-azatricyclo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>94	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Human)	BDBM14460 (4-(2-{4-[(2S)-6,15-dibromo-13-chloro-4-azatricyclo...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	378	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair