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BDBM144606 US8969583, 63

SMILES: NC(=O)c1c(N)snc1-c1cccc(NO)c1

InChI Key: InChIKey=JOVJBGJVLBSCJW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144606   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM144606
PNG
(US8969583, 63)
Show SMILES NC(=O)c1c(N)snc1-c1cccc(NO)c1
Show InChI InChI=1S/C10H10N4O2S/c11-9(15)7-8(14-17-10(7)12)5-2-1-3-6(4-5)13-16/h1-4,13,16H,12H2,(H2,11,15)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 1.21E+3n/an/an/an/a7.430



Allergan Inc

US Patent


Assay Description
Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...


US Patent US8969583 (2015)


BindingDB Entry DOI: 10.7270/Q2RN36JS
More data for this
Ligand-Target Pair