BDBM144697 US8952037, 70

SMILES COC(=O)N1CCC(CC1)c1cccnc1O[C@@H]1C[C@@H](C1)Nc1nc2ccccc2s1

InChI Key InChIKey=PDQMWNKSPGNNOB-CALCHBBNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144697   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM144697(US8952037, 70)
Affinity DataIC50:  3.18nMT: 2°CAssay Description:Enzyme Activity. An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 uL, of serial diluted P...More data for this Ligand-Target Pair
In DepthDetails US Patent