BDBM145211 US8952157, 402::US9303025, 402

SMILES CC1(C)CCC(CN2CCN(CC2)c2ccc(C(=O)NS(=O)(=O)c3cnc(OCC4(F)CCOCC4)c(F)c3)c(Oc3cnc(N)c(Cl)c3)c2)=C(C1)c1ccc(Cl)cc1

InChI Key InChIKey=GUXBJQFBQRRGIJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 145211   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM145211(US8952157, 402 | US9303025, 402)
Affinity DataKi:  0.0390nM ΔG°:  -14.2kcal/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 μM (2× starting concentration; 10% DMSO) and 10 μ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM145211(US8952157, 402 | US9303025, 402)
Affinity DataKi:  0.0390nM ΔG°:  -14.2kcal/moleT: 2°CAssay Description:Representative compounds were serially diluted in dimethyl sulfoxide (DMSO) starting at 50 uM (2x starting concentration; 10% DMSO) and 10 uL were tr...More data for this Ligand-Target Pair
In DepthDetails US Patent