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BDBM145274 US8952169, 53

SMILES: FC(F)(F)c1cc(ccc1OCC12CC3CC(CC(C3)C1)C2)C(=O)NS(=O)(=O)N1CCC1

InChI Key: InChIKey=HKODYJRGLNXHRW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 145274   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))
BDBM145274
PNG
(US8952169, 53)
Show SMILES FC(F)(F)c1cc(ccc1OCC12CC3CC(CC(C3)C1)C2)C(=O)NS(=O)(=O)N1CCC1
Show InChI InChI=1S/C22H27F3N2O4S/c23-22(24,25)18-9-17(20(28)26-32(29,30)27-4-1-5-27)2-3-19(18)31-13-21-10-14-6-15(11-21)8-16(7-14)12-21/h2-3,9,14-16H,1,4-8,10-13H2,(H,26,28)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 100n/an/an/an/a7.425



Xenon Pharmaceuticals Inc

US Patent


Assay Description
Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) was tritiated. Three tritiums were incorporated in plac...


US Patent US8952169 (2015)


BindingDB Entry DOI: 10.7270/Q2M04445
More data for this
Ligand-Target Pair